Chronic Fatigue Syndrome Practice Test 2025 – All-in-One Guide to Master Your Exam Preparation!

The Epstein-Barr Virus (EBV) has been implicated in the onset of Chronic Fatigue Syndrome (CFS) due to its established role in causing infectious mononucleosis, which is often reported in patients who later develop CFS. Research indicates that the initial EBV infection can trigger a cascade of immune responses and possibly lead to dysregulation that may result in persistent fatigue and other symptoms typical of CFS.

Additionally, studies have shown that a significant number of individuals diagnosed with CFS report a history of mononucleosis-like symptoms, which are commonly linked to EBV infections. This connection underscores the potential of EBV to not only cause acute illness but also to contribute to chronic health issues following the initial viral infection.

In contrast, while other viruses such as HIV, influenza, and Cytomegalovirus (CMV) can cause fatigue and have been studied concerning CFS, the strongest and most direct association with the onset of CFS is with the Epstein-Barr Virus. This highlights the specific role EBV plays in the pathway leading to the development of symptoms characteristic of Chronic Fatigue Syndrome.